Bashkir State Medical University opened the Institute of Fundamental Medicine

On July 12, a new building of Bashkir State Medical University was opened in Ufa. The Institute of Fundamental Medicine, specializing in fundamental scientific research in the field of biology, medicine and bioengineering, began its work there.

The three-stored building of BSMU with the area of 3 thousand square meters includes 6 scientific laboratories. The staff of the new laboratories are mostly young scientists under 39 years old.

"Historically, universities of the republic have always been focused on the training of highly qualified personnel and today we have another direction - this is the training of modern scientists and the opportunity to produce new knowledge themselves, to study the laws of nature, pathogenetic mechanisms of disease development, the basis for the production of new drugs. Today the university is making a big step into the future. We are becoming a research university, we are becoming an international center of science. And the opening of the Institute of Fundamental Medicine with the opening of new scientific laboratories allows us to look beyond the horizon - new directions will work to obtain medical knowledge and medical technologies of tomorrow. We have become a Big University, we have broken the ceiling of 15 thousand students. We operate and treat more than 50 thousand patients in our clinics. We are becoming a university that produces not only highly qualified specialists who work in more than 100 countries, we have begun to turn into a research, intonation university producing advanced knowledge. Today the country needs new own medical products, new knowledge, medicines. The Institute of Fundamental Medicine will become a base and create conditions for our talented guys to realize their most daring ideas. Thank you very much to all those who go with us together, who go with us in life", Rector of BSMU, Academician of RAS, Professor Valentin Pavlov.

Artem Narkevich, Director of the Department of Medical Education and Personnel Policy in Healthcare of the Ministry of Health of the Russian Federation read out the congratulatory message of the Minister of Health of Russia Mikhail Murashko on the occasion of the opening of the Institute of Fundamental Medicine:

"The country faces great challenges in creating new treatment methods, medical devices and medicines, introducing the latest technologies of personalized medicine, which undoubtedly requires great efforts to develop fundamental research in medicine. The goal of medical universities today is not only to train doctors, but to create and transfer knowledge. Today, the Bashkir Medical University is developing at a very high speed, possessing a huge scientific and human resource potential, and is a leader in the share of foreign students, who will later be the guides of Russian medical technologies in their countries. Exactly a year ago, this building was undergoing reconstruction. And, Radiy Faritovich and Valentin Nikolayevich and I were discussing the future prospects of fundamental research development at Bashkir Medical University. The opening of the Institute of Fundamental Medicine is a serious step towards the creation of our own technologies in the field of biomedicine and regenerative medicine, bioprinting and nature-like technologies. I warmly congratulate everyone who was involved in the launch of the Institute of Fundamental Medicine and who will work, study and create science here".

The solemn opening ceremony with participation of BSMU rector, academician of Russian Academy of Sciences, professor Valentin Pavlov was attended by:

Radii Khabirov, Head of the Republic of Bashkortostan,

Dmitry Afanasiev, Deputy Minister of Science and Higher Education of the Russian Federation,

Artem Narkevich, Director of the Department of Medical Education and Personnel Policy in Healthcare, Ministry of Health of the Russian Federation,

Chekhonin Vladimir, Deputy President of the Russian Academy of Sciences, member of the Presidium of the Russian Academy of Sciences,

Keller Andrey, Head of FGANU "Sotsiocenter",

Bashankaev Badma, Chairman of the State Duma Committee of the Federal Assembly of the Russian Federation on Health Protection,

Lilia Gumerova, Chairman of the Committee on Science, Education and Culture of the Federation Council of the Federal Assembly of the Russian Federation,

Oleg Golov, Member of the Federation Council Committee on Federal Structure, Regional Policy, Local Self-Governance and Northern Affairs,

Fedot Tumusov, First Deputy Chairman of the State Duma Committee on Health Protection,

Mikhail Kizeyev, Member of the State Duma Committee on Health Protection of the Federal Assembly of the Russian Federation.

Saryglar Aidyn, Member of the State Duma Committee on Health Protection

Tamara Frolova, Member of the State Duma Committee of the Federal Assembly of the Russian Federation on Health Protection

Rimma Utyasheva, Member of the State Duma Committee of the Federal Assembly of the Russian Federation on Health Protection, Coordinator of the "UNITED RUSSIA" project "Healthy Future" project in RB

Grigory Seleznev Deputy Chief of Staff of the State Duma Committee on Health Protection.

"For us, the Medical University is the flagship of medical education not only for Bashkortostan and the Volga Federal District, but also for the Russian Federation as a whole. It is a University that is developing very actively. Every year we see how the infrastructure and laboratory base of the University develops. This is a great achievement. I thank you, Valentin Nikolaevich, for such a desire to develop the university. I would also like to thank on behalf of the people of the republic our medical workers for the fight against Covid, we remember and do not forget, we always keep in our hearts gratitude for the lives saved. I also want to note the contribution of doctors, employees of BSMU, who treat the wounded in the zone of SMO, take part in the project "Health Trains". I would like to say words of gratitude to the whole staff of the medical university. The opening of the Institute of Fundamental Medicine will give another powerful impetus to the development of science and medical education", the Head of RB Radiy Khabirov.

The new Institute includes advanced laboratories: the Laboratory of Nature-like Materials specializes in the creation of an innovative biomaterial based on spider web silk for the purpose of application in regenerative medicine and tissue engineering. In the lab, scientists are studying the biological and mechanical properties of in-vitro spider silk on human stem cells. The study of spider web fiber structure is promising, as there are many ways to use this material, for example, to make gels for 3D printing. Eight female spiders of the genus Chilobrachuc dyscolus live in the laboratory in terrariums specially equipped for experiments. Every day the laboratory staff examines the filaments of tarantulas brought from Southeast Asia - Vietnam. Much work is being done in the laboratory to identify the best way to sterilize the webs.

The idea to use the web as a biomaterial was brought to the University by the rector of BSMU. Academician of the Russian Academy of Sciences, Professor Valentin Pavlov.

In the future, scientists of the laboratory are preparing to create a wound-healing dressing and suture material using spider web silk. The project is implemented at the university within the framework of the Russian Ministry of Education and Science's program "Priority - 2030", the national project "Science and Universities".

The laboratory of chromatographic and spectral research methods is engaged in the identification of pathology markers such as oncomarker for prostate cancer, markers of cardiovascular pathologies, analysis of the composition and purity of radiopharmaceuticals, as well as conducts quality control of drugs and pharmaceutical substances.

The laboratory of bioengineered test systems for personalized medicine is working on the "organ-on-a-chip" project. It is based on the creation of 3D-biomodels in vitro, imitating human tissues that most accurately recreate complex local biological processes of the human body. In the future, such models can be used for biomedical research and pharmacological testing of drugs, which will potentially reduce the need to use animals in laboratory research and improve the quality of research.

Cell Culture Laboratory - develops innovative cell technologies for use in regenerative medicine, immunology, oncology and will create cellular test systems for personalized diagnostics, therapeutics and preclinical research.

The Bioprinting Laboratory conducts problem-oriented scientific research in the field of bioprinting, tissue engineering, biomaterials science in order to develop and implement theoretical and engineering solutions for regenerative medicine. The main project of the laboratory is the creation of a composite bone-cartilage bioimplant for the replacement of bone-cartilage defects in osteoarthritis and post-traumatic injuries. The uniqueness of this project lies in the combination of cartilage and bone components in a single design. The cartilage and bone components are created using modern 3D printing technologies.

The morphology laboratory has 3 main missions: science, clinical work and education. By staging immunohistochemical reactions, scientists will evaluate the expression of macrophages in and around tumor tissue and which macrophages predominate, M1 or M2. So too is analyzing innate immunity in infectious pathologies such as COVID-19.

Using a Pannoramic 250 scanning microscope, BSMU scientists digitize the material, accumulate it and make markups. As a result, together with clinical data, molecular genetics results, histologic picture, there is an accumulation of databases for artificial intelligence. As a clinical work there is a lifetime diagnostic of material from the clinic of BSMU, first of all it is oncourology. In the educational cluster the whole accumulated practical and scientific layer of knowledge is seen by students, scientific circles participate in the work of the laboratory, seminars for schoolchildren are held. The digital classroom of the morphology laboratory is one of the best in Russia.

As part of the opening of the Institute, an agreement was signed with the Chinese company HUAYI ISOTOPES. The agreement provides for the development of a new strategic project to create a research and production center for nuclear medicine in the Republic of Bashkortostan as part of the implementation of the PRIORITY-2030 program.

It should be noted that the nuclear medicine industry is strictly regulated and has high entry barriers. BSMU has prerequisites for continuous development and gradual creation of production and logistics network to become one of the leaders of industrial nuclear medicine in the Volga and Urals Federal Districts. BSMU has the whole spectrum of concepts in the field of Nuclear Medicine: it is both an educational project and a construction site.