Руководитель

Кжышковска Юлия Георгиевна

Доктор биол. наук, профессор.

Заведующая лабораторией трансляционной клеточной и молекулярной биомедицины Томского Государственного университета.

Индекс Хирша (WoS) - 44

Перечень статей типа «article» / «review» WoS Q1 и Q2 за последние 5 лет:

1.      Rafikova G, Gilyazova I, Enikeeva K, Pavlov V, Kzhyshkowska Prostate Cancer: Genetics, Epigenetics and the Need for Immunological Biomarkers. J. Int J Mol Sci. 2023 Aug 14;24(16):12797. doi: 10.3390/ijms241612797. PMID: 37628978.Review. Q1.

2.      Kercheva M, Ryabov V, Gombozhapova A, Stepanov I, Kzhyshkowska J. Macrophages of the Cardiorenal Axis and Myocardial Infarction.  Biomedicines. 2023 Jun 27;11(7):1843. doi: 10.3390/biomedicines11071843. PMID: 37509483 Q1.

3.      Huang L, Tu Z, Wei L, Sun W, Wang Y, Bi S, He F, Du L, Chen J, Kzhyshkowska J, Wang H, Chen D, Zhang S. Generating Functional Multicellular Organoids from Human Placenta Villi.  Adv Sci (Weinh). 2023 Jul 12:e2301565. doi: 10.1002/advs.202301565. Online ahead of print. PMID: 37438660. Q1

4.      Larionova I, Kiselev A, Kazakova E, Liu T, Patysheva M, Iamshchikov P, Liu Q, Mossel DM, Riabov V, Rakina M, Sergushichev A, Bezgodova N, Vtorushin S, Litviakov N, Denisov E, Koshkin P, Pyankov D, Tsyganov M, Ibragimova M, Cherdyntseva N, Kzhyshkowska J. Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF.  Front Immunol. 2023 Mar 7;14:1000497. doi: 10.3389/fimmu.2023.1000497. eCollection 2023. PMID: 36960065. Q1.

5.      Kazakova E, Rakina M, Sudarskikh T, Iamshchikov P, Tarasova A, Tashireva L, Afanasiev S, Dobrodeev A, Zhuikova L, Cherdyntseva N, Kzhyshkowska J, Larionova I. Angiogenesis regulators S100A4, SPARC and SPP1 correlate with macrophage infiltration and are prognostic biomarkers in colon and rectal cancers. Front Oncol. 2023 Feb 21;13:1058337. doi: 10.3389/fonc.2023.1058337. eCollection 2023. PMID: 36895491. Q2.

6.      Rafikova G, Piatnitskaia S, Shapovalova E, Chugunov S, Kireev V, Ialiukhova D, Bilyalov A, Pavlov V, Kzhyshkowska. Interaction of Ceramic Implant Materials with Immune System. J. Int J Mol Sci. 2023 Feb 20;24(4):4200. doi: 10.3390/ijms24044200. PMID: 36835610 Free PMC article. Review. Q1.

7.      Sheng Y, Peng W, Huang Y, Cheng L, Meng Y, Kwantwi LB, Yang J, Xu J, Xiao H, Kzhyshkowska J, Wu Q. Tumor-activated neutrophils promote metastasis in breast cancer via the G-CSF-RLN2-MMP-9 axis.  J Leukoc Biol. 2023 Mar 29;113(4):383-399. doi: 10.1093/jleuko/qiad004. PMID: 36801950. Q2.

8.      Larionova I, Patysheva M, Iamshchikov P, Kazakova E, Kazakova A, Rakina M, Grigoryeva E, Tarasova A, Afanasiev S, Bezgodova N, Kiselev A, Dobrodeev A, Kostromitskiy D, Cherdyntseva N, Kzhyshkowska J.  PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse.  Front Immunol. 2023 Jan 17;13:1080501. doi: 10.3389/fimmu.2022.1080501. eCollection 2022. PMID: 36733385. Q1.

9.      Kazakova E, Iamshchikov P, Larionova I, Kzhyshkowska J. Macrophage scavenger receptors: Tumor support and tumor inhibition.  Front Oncol. 2023 Jan 6;12:1096897. doi: 10.3389/fonc.2022.1096897. eCollection 2022. PMID: 36686729 Free PMC article. Review. Q2.

10. Kazakova A, Sudarskikh T, Kovalev O, Kzhyshkowska J, Larionova I. Interaction of tumor‑associated macrophages with stromal and immune components in solid tumors: Research progress (Review).  Int J Oncol. 2023 Feb;62(2):32. doi: 10.3892/ijo.2023.5480. Epub 2023 Jan 20. PMID: 36660926 Free PMC article. Review. Q1.

11. Matveeva O, Nechipurenko Y, Lagutkin D, Yegorov YE, Kzhyshkowska J. SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry. Front Immunol. 2022 Dec 1;13:1050478. doi: 10.3389/fimmu.2022.1050478. eCollection 2022. PMID: 36532011 Free PMC article. Review. Q1.

12. Patysheva M, Frolova A, Larionova I, Afanas'ev S, Tarasova A, Cherdyntseva N, Kzhyshkowska J. Monocyte programming by cancer therapy.  Front Immunol. 2022 Oct 20;13:994319. doi: 10.3389/fimmu.2022.994319. eCollection 2022. PMID: 36341366. Q1.

13. Kercheva M, Ryabov V, Trusov A, Stepanov I, Kzhyshkowska J. Characteristics of the Cardiosplenic Axis in Patients with Fatal Myocardial Infarction. Life (Basel). 2022 May 1;12(5):673. doi: 10.3390/life12050673. PMID: 35629341 Q2.

14. Tyurin AV, Salimgareeva MK, Miniakhmetov IR, Khusainova RI, Samorodov A, Pavlov VN, Kzhyshkowska J. Correlation of the Imbalance in the Circulating Lymphocyte Subsets With C-Reactive Protein and Cardio-Metabolic Conditions in Patients With COVID-19. Front Immunol. 2022 May 6;13:856883. doi: 10.3389/fimmu.2022.856883. eCollection 2022. PMID: 35603207. Q1.

15. Patysheva M, Larionova I, Stakheyeva M, Grigoryeva E, Iamshchikov P, Tarabanovskaya N, Weiss C, Kardashova J, Frolova A, Rakina M, Prostakishina E, Zhuikova L, Cherdyntseva N, Kzhyshkowska J. Effect of Early-Stage Human Breast Carcinoma on Monocyte Programming.  Front Oncol. 2022 Feb 14;11:800235. doi: 10.3389/fonc.2021.800235. eCollection 2021. PMID: 35237501. Q2.

16. Kercheva M, Ryabov V, Gombozhapova A, Rebenkova M, Kzhyshkowska J. Macrophages of the "Heart-Kidney" Axis: Their Dynamics and Correlations with Clinical Data and Outcomes in Patients with Myocardial Infarction. J Pers Med. 2022 Jan 18;12(2):127. doi: 10.3390/jpm12020127. PMID: 35207615. Q1.

17. Matuschik L, Riabov V, Schmuttermaier C, Sevastyanova T, Weiss C, Klüter H, Kzhyshkowska J. Hyperglycemia Induces Inflammatory Response of Human Macrophages to CD163-Mediated Scavenging of Hemoglobin-Haptoglobin Complexes.  J. Int J Mol Sci. 2022 Jan 26;23(3):1385. doi: 10.3390/ijms23031385. PMID: 35163309. Q1.

18. Volokhova AA, Fedorishin DA, Khvastunova AO, Spiridonova TI, Kozelskaya AI, Kzhyshkowska J, Tverdokhlebov SI, Kurzina I. Reactive Magnetron Plasma Modification of Electrospun PLLA Scaffolds with Incorporated Chloramphenicol for Controlled Drug Release.  Polymers (Basel). 2022 Jan 18;14(3):373. doi: 10.3390/polym14030373. PMID: 35160362 . Q1.

19. Silva-Bermudez LS, Sevastyanova TN, Schmuttermaier C, De La Torre C, Schumacher L, Klüter H, Kzhyshkowska J. Titanium Nanoparticles Enhance Production and Suppress Stabilin-1-Mediated Clearance of GDF-15 in Human Primary Macrophages.  Front Immunol. 2021 Dec 15;12:760577. doi: 10.3389/fimmu.2021.760577. eCollection 2021. PMID: 34975851. Q1.

20. Carai P, Papageorgiou AP, Van Linthout S, Deckx S, Velthuis S, Lutgens E, Wijnands E, Tschöpe C, Schmuttermaier C, Kzhyshkowska J, Jones EAV, Heymans S. Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis. J Mol Cell Cardiol. 2022 Apr;165:31-39. doi: 10.1016/j.yjmcc.2021.12.009. Epub 2021 Dec 28. PMID: 34968453. Q1.

21. Gvaramia D, Kern J, Jakob Y, Tritschler H, Brenner RE, Breiter R, Kzhyshkowska J, Rotter N. Modulation of the inflammatory response to decellularized collagen matrix for cartilage regeneration. J Biomed Mater Res A. 2022 May;110(5):1021-1035. doi: 10.1002/jbm.a.37349. Epub 2021 Dec 29. PMID: 34967101. Q2.

22. Spiekman M, Francia DL, Mossel DM, Brouwer LA, Diercks GFH, Vermeulen KM, Folkertsma M, Ghods M, Kzhyshkowska J, Klüter H, Krenning G, van der Lei B, Harmsen MC. Autologous Lipofilling Improves Clinical Outcome in Patients With Symptomatic Dermal Scars Through Induction of a Pro-Regenerative Immune Response.  Aesthet Surg J. 2022 Mar 15;42(4):NP244-NP256. doi: 10.1093/asj/sjab280. PMID: 34270698. Q1.

23. Larionova I, Kazakova E, Gerashchenko T, Kzhyshkowska J.New Angiogenic Regulators Produced by TAMs: Perspective for Targeting Tumor Angiogenesis. Cancers (Basel). 2021 Jun 29;13(13):3253. doi: 10.3390/cancers13133253. PMID: 34209679. Q2.

24. Barthes J, Lagarrigue P, Riabov V, Lutzweiler G, Kirsch J, Muller C, Courtial EJ, Marquette C, Projetti F, Kzhyskowska J, Lavalle P, Vrana NE, Dupret-Bories A. Biomaterials. Biofunctionalization of 3D-printed silicone implants with immunomodulatory hydrogels for controlling the innate immune response: An in vivo model of tracheal defect repair.  2021 Jan;268:120549. doi: 10.1016/j.biomaterials.2020.120549. Epub 2020 Nov 24. PMID: 33278685. Q1.

25. Stankevich KS, Kudryavtseva VL, Bolbasov EN, Shesterikov EV, Larionova IV, Shapovalova YG, Domracheva LV, Volokhova AA, Kurzina IA, Zhukov YM, Malashicheva AB, Kzhyshkowska JG, Tverdokhlebov SI. Modification of PCL Scaffolds by Reactive Magnetron Sputtering: A Possibility for Modulating Macrophage Responses.  ACS Biomater Sci Eng. 2020 Jul 13;6(7):3967-3974. doi: 10.1021/acsbiomaterials.0c00440. Epub 2020 Jun 5. PMID: 33463309. Q2.

26. Larionova I, Tuguzbaeva G, Ponomaryova A, Stakheyeva M, Cherdyntseva N, Pavlov V, Choinzonov E, Kzhyshkowska J. Tumor-Associated Macrophages in Human Breast, Colorectal, Lung, Ovarian and Prostate Cancers. Front Oncol. 2020 Oct 22;10:566511. doi: 10.3389/fonc.2020.566511. eCollection 2020. PMID: 33194645. Q2.

27. Kercheva M, Gusakova AM, Ryabova TR, Suslova TE, Kzhyshkowska J, Ryabov VV. Serum Levels of Bone Morphogenetic Proteins 2 and 4 in Patients with Acute Myocardial Infarction. Cells. 2020 Sep 27;9(10):2179. doi: 10.3390/cells9102179. PMID: 32992577. Q2.

28. Will PA, Rafiei A, Pretze M, Gazyakan E, Ziegler B, Kneser U, Engel H, Wängler B, Kzhyshkowska J, Hirche C. Evidence of stage progression in a novel, validated fluorescence-navigated and microsurgical-assisted secondary lymphedema rodent model. PLoS One. 2020 Jul 23;15(7):e0235965. doi: 10.1371/journal.pone.0235965. eCollection 2020. PMID: 32701960. Q1.

29. Mossel DM, Moganti K, Riabov V, Weiss C, Kopf S, Cordero J, Dobreva G, Rots MG, Klüter H, Harmsen MC, Kzhyshkowska J. Front Immunol. 2020 Jun 2;11:1071. doi: 10.3389/fimmu.2020.01071. Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions. eCollection 2020. PMID: 32582175. Q1.

30. Larionova I, Kazakova E, Patysheva M, Kzhyshkowska J. Transcriptional, Epigenetic and Metabolic Programming of Tumor-Associated Macrophages.  Cancers (Basel). 2020 May 29;12(6):1411. doi: 10.3390/cancers12061411. PMID: 32486098. Q2.

31. Kzhyshkowska J, Larionova I, Liu T. YKL-39 as a Potential New Target for Anti-Angiogenic Therapy in Cancer.  Kzhyshkowska J, Larionova I, Liu T. Front Immunol. 2020 Jan 22;10:2930. doi: 10.3389/fimmu.2019.02930. eCollection 2019. PMID: 32038607. Q1.

32. Patysheva M, Stakheyeva M, Larionova I, Fedorov A, Kzhyshkowska J, Cherdyntseva N. Cytostatic cancer therapy modulates monocyte-macrophage cell functions: how it impacts on treatment outcomes. Exp Oncol. 2019 Sep;41(3):248-253. doi: 10.32471/exp-oncology.2312-8852.vol-41-no-3.13597. PMID: 31569929.

33. Babyshkina N, Vtorushin S, Dronova T, Patalyak S, Slonimskaya E, Kzhyshkowska J, Cherdyntseva N, Choynzonov E. Impact of estrogen receptor α on the tamoxifen response and prognosis in luminal-A-like and luminal-B-like breast cancer. Clin Exp Med. 2019 Nov;19(4):547-556. doi: 10.1007/s10238-019-00583-6. Epub 2019 Sep 27. PMID: 31562548. Q2.

34. Yin S, Wang N, Riabov V, Mossel DM, Larionova I, Schledzewski K, Trofimova O, Sevastyanova T, Zajakina A, Schmuttermaier C, Gratchev A, Flatley A, Kremmer E, Zavyalova M, Cherdyntseva N, Simon-Keller K, Marx A, Klüter H, Goerdt S, Kzhyshkowska J. SI-CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor-associated macrophages. Int J Cancer. 2020 Mar 1;146(5):1396-1408. doi: 10.1002/ijc.32685. Epub 2019 Dec 4. PMID: 31525266. Q1.

35. Ščigalková I, Bystroňová J, Kovářová L, Pravda M, Velebný V, Riabov V, Klüter H, Kzhyshkowska J, Vrana NE. The effect of healing phenotype-inducing cytokine formulations within soft hydrogels on encapsulated monocytes and incoming immune cells.  RSC Adv. 2019 Jul 10;9(37):21396-21404. doi: 10.1039/c9ra02878a. eCollection 2019 Jul 5. PMID: 35521319 . Q2.

36. Larionova I, Cherdyntseva N, Liu T, Patysheva M, Rakina M, Kzhyshkowska J. Interaction of tumor-associated macrophages and cancer chemotherapy. Oncoimmunology. 2019 Apr 13;8(7):1596004. doi: 10.1080/2162402X.2019.1596004. eCollection 2019. PMID: 31143517. Q1.

37. Rendra E, Riabov V, Mossel DM, Sevastyanova T, Harmsen MC, Kzhyshkowska J. Reactive oxygen species (ROS) in macrophage activation and function in diabetes. Immunobiology. 2019 Mar;224(2):242-253. doi: 10.1016/j.imbio.2018.11.010. Epub 2018 Dec 1. PMID: 30739804. Q3.

38. Korytina GF, Akhmadishina LZ, Aznabaeva YG, Kochetova OV, Zagidullin NS, Kzhyshkowska JG, Zagidullin SZ, Viktorova TV. Associations of the NRF2/KEAP1 pathway and antioxidant defense gene polymorphisms with chronic obstructive pulmonary disease. Gene. 2019 Apr 15;692:102-112. doi: 10.1016/j.gene.2018.12.061. Epub 2019 Jan 12. PMID: 30641209.  Q2.